Hilton Jacksonville at Mayo Clinic Set to Debut October 2025 Offering a Modern, Coastal Take on Hospitality in Northeast Florida

Something exciting is taking shape on Transformation Way. Slated to open in October 2025, Hilton Jacksonville at Mayo Clinic is gearing up to become one of Northeast Florida's most anticipated hotel openings, a sophisticated escape offering world-class service with relaxing coastal charm.

Just minutes from Jacksonville's sun-drenched beaches, championship golf courses, and vibrant cultural attractions, the first Hilton Hotels & Resorts property in Jacksonville will feature eight stories and 252 guest rooms, spanning over 184,000 square feet. The property will welcome leisure travelers, corporate guests, wellness seekers, visiting families, and everyone in between. The hotel will be managed by Concord Hospitality, an award-winning hotel management company known for its high-touch service and partnership with leading hospitality brands.

Guests can expect a full-service experience with standout amenities including:

• 21 spacious suites
• More than 21,000 square feet of event space, including a grand pillarless ballroom, junior ballroom, boardrooms, and a spectacular 5,000 square feet outdoor event lawn overlooking serene water
• Resort-style outdoor heated pool and a covered outdoor terrace surrounded by lush landscaping
• 24-hour expansive fitness center
• Coastal Kitchen, the hotel's signature restaurant that makes use of locally sourced and organic ingredients to support its wellness-focused menu of breakfast, lunch, and dinner offerings centered on fresh seafood, artisanal pizzas, seasonal salads, and premium steaks.
• A sleek coffee shop in the lobby, offering smoothies, locally sourced coffee, and grab-and-go breakfast and lunch items
• Full room service, offering guests comfort and quality any time of day

Inspired by the landscape of trees and tranquil ponds, the hotel's design by DLR Group uses warm textures, glass, and clean modern lines to reflect the area's natural beauty while delivering a refined, peaceful guest experience.

Hilton Jacksonville at Mayo Clinic is located at 4745 Transformation Way, Jacksonville, FL 32224. For more information, visit hilton.com. For reservations, call + 904 929 9000, or email [email protected].

Hotel website